RSS 1.0Lee Kong Chian School of Medicine (LKCMedicine)
Recent Submissions
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Synergy of novel cationic polymer with antibiotics in pseudomonas aeruginosa
(2017)This study attempts to replicate and quantify the interaction between a novel polymer, 70-5, synthesized by SCBE (School of Chemical and Biochemical Engineering) and antibiotics of several different classes against ... -
Potentially modifiable risk factors of frailty in community-dwelling older fallers
(2017)Background and Aim: Falls in the older adult are associated with significant morbidity, functional decline and institutionalization. As the population ages, falls are likely to increase in incidence. Thus, prevention is ... -
Identifying the impact of pre-operative assessment scores on functional recovery of the elderly colorectal surgical patient
(2017)Background: With the emergence of an aging population, there is an increased need to risk stratify and optimize surgical management in the elderly due to their poorer baseline functional status as well as a higher risk ... -
Evaluation of the prevalence of hearing and balance symptoms in patients with autoimmune rheumatic diseases presenting to the Rheumatology Department using the Dizziness Handicap Inventory (DHI) and Hearing Handicap Inventory Adults/Elderly (HHIA/E) – a pilot study
(2017)Introduction Autoimmune Inner Ear Disease (AIED) is a diagnosis which suggests autoimmune mediation of inner ear pathology, but is as yet not a widely recognized clinical entity. This study aims to determine the prevalence ... -
Understanding why women with breast cancer present late
(2017)Introduction: Breast cancer (BC) has the highest incidence and mortality of all cancers among women in Singapore. Despite increasing affluence, education, healthcare accessibility, and the institution of nation-wide ... -
Factors associated with performance in clinical reasoning tests of neurological localization : a study in internal medicine residents
(2017)Background: Clinical Reasoning is the cognitive process of weighing clinical information together with past experience to evaluate diagnostic and management dilemmas. A variety of paper tests have been validated to assess ... -
Systematic review on volume-outcome relationship in radical prostatectomy
(2017)Background: Radical prostatectomy (RP) is one of the most complex urological procedures performed. A 2013 systematic review demonstrated that higher annual volume of cases undertaken by both surgeons and hospitals is ... -
Identifying candidate proteins that undergo activity-dependent synapse to nucleus translocation in hippocampal neurons
(2017)Previous studies have explored the mechanisms that proteins from the post-synaptic terminal utilise during retrograde transport to the nucleus (1,2) and their role on learning and memory formation in neurons (3–5), but ... -
Exploring the sources of support for caregivers in Singapore
(2017)It is during the two ends of the age spectrum that care requirements are at its greatest. Though the elderly form the largest proportion of care-recipients, children – particularly those with special health care needs – ... -
A micro-analytical approach to cognitive engagement during Team Based Learning (TBL) in an undergraduate medical curriculum
(2017)Purpose: This study aimed to determine and analyze the levels of cognitive engagement during Team Based Learning (TBL) phases in an undergraduate medical curriculum. Methods: The TBL phases were Preparation (Prep), ... -
Determination of Apolipoprotein C3 levels in patient plasma and tear samples
(2017)Apolipoprotein C3 (ApoC3) has been shown to be consistently associated with multiple diseases, namely hypertriglyceridemia, non-alcoholic fatty disease, ischemic vascular disease, and type 2 diabetes mellitus. However these ... -
Situational interest in team-based learning
(2017)Purpose: Team-Based Learning (TBL) is a teaching strategy that has become increasingly popular in medical education. While studies have been done regarding outcomes from TBL, there is a lack of research about the TBL process ... -
Identification of pseudomonas aeruginosa via fast PCR in less than 5min
(2017)Pseudomonas aeruginosa(PSA) plays a prominent role in infections, especially in chronic illnesses like Chronic Obstructive Pulmonary Disease and the immunocompromised. Rapid detection of PSA would play an important role ... -
Analyzing medical personnel’s perceptions of online health rumors
(2017)The internet is a hotbed for health rumors which are easily accessible to the public. Rumors are information without verifiable evidence. They can influence public behavior depending on how people perceive them. Prior ... -
Developing a low-cost dermatoscope
(2017)Dermatoscopes play a burgeoning role in dermatology, but are prohibitively expensive for non-dermatologists, especially medical undergraduates and generalists in resource-poor settings. A low-cost solution lies in developing ... -
Ethical issues in HIV medicine
(2017)Vertical transmission of HIV has declined steadily over the years with the introduction of antiretroviral therapy (ART) during pregnancy. However, an ethical dilemma arises when a mother refuses ART and increases the risk ... -
Gamification of male urinary catheterisation : a multi-disciplinary experience in evidence-based conceptualisation of an educational game
(2017)Objective: To conceptualise an educational game on male urinary catheterisation for undergraduate medical students. Background: There is a plethora of desirable outcomes of educational games, including motivation-driven ... -
Hip and prosthetic dislocation presenting to emergency department of Tan Tock Seng Hospital
(2017)Introduction: Native and prosthetic hip dislocations are emergencies. With an ageing society that is living longer, the increased incidence of hip fracture and resultant prosthetic implantation has led to a rise in prosthetic ... -
Can type 2 diabetic serum alter macrophage phenotype
(2017)Inflammation, caused by obesity and metabolic changes, contributes to the pathogenesis of Type 2 diabetes (T2D) via many mechanisms and may be mediated by circulating cytokines and inflammatory markers produced by ... -
To analyze the effects of leucine-rich alpha-2 glycoprotein-1 (LRG1) on angiogenesis in diabetes associated ischemic heart disease
(2017)The incidence of ischemic heart disease (IHD) is rising globally. Current treatment strategies do not alter the underlying process or the natural progression of the disease. Furthermore, not all patients can undergo ...
