dc.contributor.authorKoh, Jackson Peng Fei
dc.date.accessioned2016-05-15T09:09:09Z
dc.date.available2016-05-15T09:09:09Z
dc.date.issued2016-05-11
dc.identifier.citationKoh, J. P. F. (2016). Synthesis of high value chemicals from biomass platform chemicals. Doctoral thesis, Nanyang Technological University, Singapore.
dc.identifier.urihttp://hdl.handle.net/10356/67322
dc.description.abstractIn this thesis, the conversion of biomass to several high value chemicals via versatile and synthetically useful platform chemicals was described. These high value chemicals include a common intermediate that allow access to several potent NK1 receptor antagonists which are associated with the treatment of anxiety and emesis, as well as biologically active natural products aspergillides A and B with cytotoxic activity against mouse lymphocytic leukemia cell (L1210). In particular, the syntheses of aspergillides A and B was achieved such that all of the carbons present are derived from biomass derived platform chemicals. These demonstrate the feasibility of constructing valuable biologically active compounds using a sustainable chemical feedstock like biomass.en_US
dc.format.extent15 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Science::Chemistry::Organic chemistry::Organic synthesisen_US
dc.titleSynthesis of high value chemicals from biomass platform chemicalsen_US
dc.typeThesis
dc.contributor.supervisorLoh Teck Peng (SPMS)en_US
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.description.degreeDOCTOR OF PHILOSOPHY (SPMS)en_US


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