Mutagenesis and characterization studies of E. Coli DNA-binding protein from starved cells (DPS)
Ang, Emmiline Xiao Wei
Date of Issue2010
School of Physical and Mathematical Sciences
Ferritins are proteins that form spherical protein cages surrounding nanacavities filled with iron.E.coli DNA-binding protein from starved cell (DPS), a mini-ferritin capable of self-assembling into 12-meric (twelve monomers) nanocages, was chosen as the basis for an alanine-shaving mutagenesis study to investigate the importance of key amino acid in controlling protein stability and self-assembly.
Final Year Project (FYP)