Refractive index measurement of single living cell using biophotonic chip.
Liu, Ai Qun.
Liang, Xiao Jun.
Chin, Lip Ket.
Date of Issue2004
School of Electrical and Electronic Engineering
This project combines microfluidic and micro-optical technologies to develop an integrated biophotonic chip for single cell analysis. More specifically the effective refractive index (RI) of cells is determined. The microfluidic system serves as a tool for single living cell manipulation, while the micro-optical system serves as a sensor to measure the effective RI of a single living cell in real time. By using RI as an indicator, any slight changes inside the cells can be detected. Therefore the biophotonic chip has a series of potential applications in many disease diagnostic devices in the future.
DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Nanyang Technological University