Biodegradable ocular implants
Ooi, Chui Ping
Date of Issue2001
School of Chemical and Biomedical Engineering
Cytomegalovirus (CMV) retinitis is the most common ocular infection in patients with Acquired Immune Deficiency Syndrome (AIDS), occurring in 15%-40% of AIDS patients. It will cause blindness in 3 to 6 months if left untreated. The available mode of treatments ranges from intravenous to implants for localised drug delivery. However, several problems have been associated with these treatments and a sustained-release biodegradable device is needed to decrease these risks and produce a longer therapeutic effect.
Nanyang Technological University