Nasopharyngeal cancer diagnosis with optical coherence tomography.
Ng, Beng Koon.
Sirajudeen Gulam Razul.
Date of Issue2007
School of Electrical and Electronic Engineering
Two optical coherence tomography (OCT) systems were implemented in this work to extend the scope of an on-going research project, funded by the Singapore Cancer Syndicate to investigate the use of OCT for early nasopharyngeal cancer (NPC) diagnosis. The first OCT system is designed around a 1300 nm broadband superluminescence diode (SLD) source using the time-domain method. An axial resolution of 10 μm and an imaging depth of more than 2.5 mm were obtained with this system. An existing time-domain 800 nm OCT system based on a Ti:Sapphire laser source is modified into a Fourier-domain system using a nearinfrared (NIR) spectrometer. This eliminates the need for mechanical scanning on the reference arm of the OCT system and improves the imaging time by a factor of 3.7.
DRNTU::Engineering::Electrical and electronic engineering::Control and instrumentation::Medical electronics